Tương tự như codein, dược động học có thể đóng vai trò trong việc ức chế hệ thần kinh trung ương. Trẻ sơ sinh có vẻ đặc biệt nhạy cảm với tác dụng của liều nhỏ của thuốc giảm đau gây nghiện.
Therefore, using dihydrocodeine needs to be avoided whilst the patient is using MAOIs and for 2 weeks following MAOI discontinuation.
Concomitant use of Dihydrocodeine tablets and sedative medicines which include benzodiazepines or similar drugs increases the danger of drowsiness, difficulties in breathing (respiratory depression), coma and may be lifethreatening.
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Patients could notice that treatment is considerably less helpful with Continual use and Categorical a have to increase the dose to obtain the exact same amount of pain Regulate as initially knowledgeable.
Dihydrocodeine might result in the release of histamine; consequently this product really should not be administered during an asthmatic assault and may be administered with warning in patients with allergic disorders.
Pain medications work finest if they are applied as the very first signs of pain arise. In the event you wait right up until the pain has worsened, the medication may well not work too.
Concomitant use of Dihydrocodeine and sedative medicines which include benzodiazepines or linked drugs might result in sedation, respiratory
Usually do not continue to keep out-of-date or undesirable medicines. Take them to your neighborhood pharmacy which will eliminate them for you.
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Gastric contents may possibly therefore must be emptied, as This may be practical in eliminating unabsorbed drug, especially when a prolonged launch formulation has been taken.
Do not take St John's wort, the herbal treatment for depression, Whilst you're getting taken care of with sertraline as this will likely boost your hazard of side effects.
Pethidine, tramadol and dextromethorphan (a standard ingredient in cough medicines) are opioids with a high possibility of causing serotonin syndrome when utilised with serotonergic antidepressants.
A Health care Specialist ought to be consulted in advance of taking any drug, transforming any diet regime or commencing or discontinuing any course of treatment.